Plans for a £100m development have been submitted to Brighton and Hove council.
The scheme, on a council-owned site on Circus Street in Brighton, is being built by developers Cathedral Group and McLaren Property.
It includes a base for South East Dance and a library and teaching building for the University of Brighton. It also involves 142 homes and more than 3,000 sqm of offices, plus halls of residence for up to 486 students.
The majority of the buildings are designed to reach either BREEAM Excellent or Code for Sustainable Homes Level 4.
The scheme was designed by architecture practice shedkm.
The council is about to start a statutory public consultation on the planning application. The developers hope the scheme will be approved early next year and that construction will begin next summer.