Canary Wharf Group has announced plans to begin construction of a 20-storey tower this autumn.
The move comes after the group agreed terms with the European Medicines Agency to pre-let 23,225 sq m of space, or about half of the building being constructed at 25 Churchill Place.
The project is the last tower to be constructed from the original master plan for the regeneration of London Docklands, drawn up nearly 25 years ago.
The project is expected to create around 1,000 construction jobs.
Work to the substructure has already been completed and hand over of the entire building is expected on 1 January 2015.
Canary Wharf Group chairman and chief executive George Iacobescu said: “We are very pleased to provide the European Medicines Agency with a building that responds to their new requirements, offering new technology and significant organisational and environmental efficiencies. It demonstrates our continued ability to deliver superior office space and infrastructure for a broad range of world-class organisations.”
Construction of the shell and core and fit-out will be undertaken by Canary Wharf Group.
The architects are Kohn Pedersen Fox Associates.