Around 60 homes are flooded in Armitage Bridge near Huddersfield, West Yorkshire Fire and Rescue Service said.
Meanwhile, in Silsden 100 people were being evacuated from a factory.
The Environment Agency (EA) has issued warnings for several catchments and communities were today urged to remain vigilant as the threat of flooding remains with river levels expected to peak tomorrow.
Officers from the EA said they were particularly concerned with the Rivers Aire and Calder in West Yorks after rainfall totals of 30 to 50mm of rain were forecast for today.
Mark Tinnion, regional flood risk manager for the EA, said: “Some flooding is likely to happen in the region, but at this stage it is not thought to be as widespread or significant as the summer floods.
“We have been monitoring the situation very closely and we are starting to patrol areas at risk.”
South Yorkshire Police warned drivers to take care after reports of standing water in Rossington and the A6023 at Mexborough.
A woman and child had to be rescued by Humberside firefighters after their car got stuck in flood water on the B1246 road from Pocklington to Warter.
In York, the Foss Barrier is closed and pumps have been deployed by the EA at Elvington, Wood Dyke, Burr Dyke and Naburn.
As the week progresses, river levels on the Ouse and Derwent are expected to rise. Levels at York are expected to be very high later in the week after the rain has worked its way downstream.