AMEC has bagged a £25 million research building for Manchester University.
It is the third job the contractor has picked up as part of the university's £300 million redevelopment.
The firm has already been taken on for a £40 million biomedical research building and £20 million humanities building in the redevelopment project, which followed the merger of UMIST with the University of Manchester.
Amec's most recent success in the scheme came at the expense of rival bidders HBG, Norwest Holst, Shepherd and Sir Rober t McAlpine.
The building, known as SEP, is the last of the phase one project to start. It was in a previous batch of contracts described as the Biosciences Research Building Wing E, but was scaled down by around £10 million and retendered separately.
Other firms that have benefited from the merger are Laing O'Rourke, which has won a £45 million deal to build a new nursing school, and HBG, which grabbed the £35 million maths building contract.