The Reading-based firm, which trades as Plumb Center and Build Center, said the moves reflected its expectations for a further decline in trading.
The company also shed 5,050 positions between August and the end of October, mainly in North America.
Wolseley, which operates more than 1,900 branches in the UK and Ireland, said the latest job cuts would be phased over the next few months,
The job cuts are expected to reduce annual costs at the company by £80 million.
The pressure on Wolseley to reduce overheads was highlighted by first quarter figures today, with group trading profits down 30 per cent due to lower profitability at its UK and American operations.
The company said: "Our objective remains to ensure the appropriate sizing of the cost base in line with the expected market environment."
Wolseley said revenues in the UK and Ireland division decreased by about 10 per cent with trading profits down by around 65 per cent in the three months to October 31.
The company said its building materials brands such as Build Center and Brooks in Ireland continued to be affected by the rapid deterioration in new residential construction.