Engie has secured the design-and-construct package on the regeneration scheme in Tower Hamlets.
The development near St Katherine’s Dock for developer L&Q has already seen 18 months of archaeological work and demolition completed.
Engie, which bought the regeneration arm of Keepmoat last year for £330m, is now beginning main construction work.
The mixed-use development includes building 65 mixed-tenure properties and four commercial units.
Engie regional managing director Dan Germann said: “Considerable work has gone on behind the scenes to bring this project to fruition and we have been involved from day one. It has been a complex process as it required demolition work.”
Engie has also committed to investing £90,000 to offer employment and training opportunities for local people throughout the duration of the project.
The new block of apartments will be known as Tower Reach and work is expected to complete in May 2020.