Morgan Est has won a £100 million contract to work on the A1 Dishforth to Barton project later this month.
The firm will work alongside Carillion on the scheme, which has a total value of £318 million.
The works will include upgrading the two-lane dual carriageway to a three-lane motorway as well as installing low-noise surfacing to benefit local residents.
Work is scheduled to start in March 2009, and is due to finish in 2012.
Morgan Sindall chief executive Paul Smith said: “This is a major road project and we have been working on the contract with the Highways Agency since 2004. Morgan Est has an excellent track record in delivering infrastructure projects of this type and we are excited to be working alongside Carillion.”