Amey has won a £325m 15-year contract from Highways England to service the road network around Liverpool and Manchester.
The contract for the Area 10 network serves routes connecting Manchester, Liverpool and surrounding areas and will see Amey take responsibility for all routine and cyclical maintenance on the trunk road and motorway network.
The deal covers Cheshire, Merseyside, Greater Manchester and South Lancashire and will begin in April 2019.
A joint venture between Balfour Beatty and Mott McDonald has overseen maintenance of the network since 2012 and had secured a £115m extension to March 2019 earlier this year.
Amey currently maintains Highways England Area 7, which covers a 787 km network, and is responsible for designing maintenance and improvement schemes for nearly 658 km of roads in Areas 13 and 14.
Under the new contract there will be a greater focus on bringing services in-house, including winter maintenance.
To deliver the service, Amey will be recruiting 45 new employees from the North-west to join the present team across a variety of roles.
Amey chief executive Andy Milner said: “Working together, listening and learning from our clients and customers, we have reshaped our highways business to put collaboration and service delivery at the heart of our approach.
“This approach is the basis of developing the Area 10 collaborative model with Highways England and the supply chain to deliver services for the communities of the North-west.”